I can't believe people haven't mentioned some of these.
1.) Kirk Hammet - Metallica Best Solo: Battery or One
2.) Keith Richards - Rolling Stone Best Solo: Sympathy For The Devil
3.) Jimmy Page - Led Zeppelin Best Solo: Stairway To Heaven
4.) Dimebag Darrell - Pantera (R.I.P) Best Solo: Floods or Cemetary Gates
5.) Prince - Prince and The Revoloution (There just isn't an instrument this man isn't one of the best at.) Best Solo: Little Red Corvette or Purple Rain during the Super Bowl XL Halftime Show.